Lucille Ball

It's the late 1920s. Upon the death of wealthy Chicagoan Edward Dennis, his nine-year old son Patrick Dennis becomes the ward of their only living relative, Edward's equally wealthy New York residing sister, Mame Dennis. Edward's will states that Patrick is to be raised Protestant in a "traditional" manner and that the trustee, Mr. Babcock with the Knickerbocker Bank, will pay Mame for expenses incurred in raising Patrick, he having the right of refusal to pay if he deems that the spirit of Edward's will is not honored. Mr. Babcock and Patrick's longtime nanny, the timid Agnes Gooch, are to ensure that Patrick is raised correctly. Edward included these stipulations in his will as he knows his sister is a flamboyant, free wheeling and eccentric woman who can be considered anything but traditional or conventional. Despite the disruption each provides in the other's life, Mame and Patrick form a loving, supportive relationship. Mame wants to provide her sense of guidance to Patrick, which means exposing him to a broad spectrum of all that life has to offer. That changes when Mr. Babcock learns what is going on, and the stock market crashes resulting in Mame losing all her money, the events in combination leading to Mr. Babcock taking Patrick away to enroll him in boarding school away from Mame's daily influence. Although not for herself, Mame realizes that she needs money to get Patrick back and support who she considers her entire family, which includes Agnes and her faithful butler, Ito. She may get a little help in the matter from her best friend, Broadway actress Vera Charles, and a southerner she meets named Beauregard Jackson Pickett Burnside. Over the next several years, Mame's influence on those around her, including Patrick, is presented, although those relationships are not always smooth sailing, especially as Patrick grows into a man with a mind of his own.

In WWII Pat Jamieson is a scientist working, with Government support, on a high-altitude oxygen mask for fighter pilots. But he has nowhere to conduct his research in secret until he meets Jamie Rowan, a woman with an unused house with a scientist's basement. Jamie has no hopes of marrying for love (and neither does Pat) but Jamie wants to help the war effort and she likes this quirky scientist and his dog, so to satisfy the proprieties they agree on a business arrangement: a marriage of convenience and partnership. They happily work on oxygen mixes instead of honeymooning. But as the footing of their relationship begins warm up, Jamie is courted by another man and the old flame that broke Pat's heart is back in his life. It will take a sleepwalking ruse, dodging in and out of doors, and a working oxygen mask to get them together again.

Private investigator Bradford Galt has moved to New York from San Fransisco after serving a jail term on account of his lawyer partner Tony Jardine. When he finds someone is tailing - and possibly trying to kill him, Galt believes Jardine is behind it. As he finds there is rather more to it, he is increasingly glad to have his attractive new secretary Kathleen around, for several reason.